Tag Archives: trait

Why malaria sickle cell trait

The high prevalence of HbS in sub-Saharan Africa and some other tropical areas is almost certainly due to the protection against malaria afforded to heterozygotes [ 1 — 3, 5 ]. Haematology in Africa. Table 1 Hypothesized protective mechanisms of sickle cell trait HbAS against malaria Full size table. Chloroquine and Hydroxychloroquine New! Balanced Polymorphism… Read More »